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An Explainable Epidemiology System for Vaccine Safety and Proactive Care

Primary supervisor

MD SAMIULLAH

This project aims to develop an explainable epidemiology system that combines generative AI, biostatistics, and epidemiological reasoning to support healthcare analysis and decision-making. The system will take structured health data as input, analyse it multimodally, and build a knowledge base that can be queried by epidemiologists and health researchers. The goal is to enable users to ask practical questions such as whether a vaccine or exposure is associated with increased risk, how strong the signal is, which methods support the finding, and what assumptions or parameter settings were used.

The project is designed to support both vaccine safety surveillance and proactive care in general practice. In vaccine safety, it can help identify potential adverse event signals and explain why they may warrant attention. In general practice, it can help identify patients at rising risk of deterioration, support earlier intervention, and reduce administrative burden by surfacing clinically relevant patterns in a transparent and auditable way. The emphasis is on interpretability, trust, and practical usefulness rather than black-box prediction.

Aim/outline

  • Design and prototype an explainable system that can ingest formatted health data and generate structured, queryable outputs.
  • Support epidemiological reasoning by enabling risk-related and signal-detection questions with transparent methods and explanations.
  • Evaluate usefulness and interpretability for real-world healthcare use cases such as vaccine safety and proactive general practice care.

Required knowledge

  • Programming skills in Python or R
  • Basic understanding of data wrangling and structured data analysis
  • Interest in AI / machine learning / generative AI
  • Willingness to learn biostatistics and epidemiology
  • Familiarity with databases, knowledge bases, or knowledge graphs is an advantage
  • Good analytical thinking and an interest in health or biomedical applications
  • Awareness of research ethics, privacy, and reproducibility